Standard siRNA design tools apply basic thermodynamic rules without comprehensive transcriptome-wide off-target evaluation or SNP awareness — introducing risk into every experiment.
Publicly available designers rarely account for all known transcript isoforms, leaving predicted activity uncertain and knockdown results inconsistent across experimental contexts.
Without rigorous homology checks across Human, Mouse, and NHP, you risk repeating entire validation campaigns when moving between model systems.
Built by siRNA drug development veterans. Pure in silico design — no synthesis, no wet-lab. Your IP, your sequences, your science.
Homology analysis across Human, Mouse, and NHP transcriptomes so your sequences work across all model systems from day one.
Comprehensive off-target evaluation combined with SNP-aware analysis — every candidate assessed for SNPs that could impact binding and specificity.
Pipeline covers all known transcript isoforms of your target gene, ensuring predicted activity is robust and not limited to a single transcript variant.
Default settings calibrated to deliver a curated shortlist with high real-world hit rates — detailed in silico results ready for hit selection and lead optimization.
Create your account and enter your target gene, species, and preferred parameters directly in the platform.
Our bioinformatics algorithm runs cross-species homology, off-target, SNP, and isoform analysis automatically.
Receive a ranked shortlist of siRNA candidates with a full analysis report, ready for synthesis ordering.
Choose the tier that matches your research stage.
Ideal for academic researchers and early-stage target validation who need a focused, high-quality shortlist.
SGD 2,000
per target gene
Designed for drug discovery programs requiring comprehensive sequence coverage for lead optimization and library generation.
SGD 6,000
per target gene
Select your service tier after signing up
ⓘ Terms of Service
Each target gene is designed once per customer — the platform will not generate additional sequences for a target already served.
This service does not include Freedom to Operate (FTO) analysis. It is the user's sole responsibility to evaluate IP freedom for any sequences generated.
All intellectual property of the generated sequences belongs exclusively to the user. siDesign Academy does not retain or claim any IP rights over output sequences.
If you have any questions about the platform, our methodology, or which service tier is right for you — we're happy to help before you create an account.
Email us directly
support@oligogenix.com
We respond promptly
All enquiries are answered within 24 hours
Thanks for reaching out. We'll get back to you within 24 hours. In the meantime, feel free to sign up and explore the platform.